Product Overview
ALLO-2 | T14188 | TargetMol Chemicals
CAS: 1357350-60-7
Smiles: FC(F)(F)Oc1ccc(cc1)-c1ccnc(Nc2ccc3[nH]ncc3c2)n1
Formula: C18H12F3N5O
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened|||Smo
Receptor: N/A
Bioactivity: ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
Molecular Weight: 371, 323