Product Overview
Aloisine A | T21377 | TargetMol Chemicals
CAS: 496864-16-5
Smiles: CCCCc1c([nH]c2nccnc12)-c1ccc(O)cc1
Formula: C16H17N3O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM).
Molecular Weight: 267, 332