Product Overview
Alphitolic acid | TN1379 | TargetMol Chemicals
CAS: 19533-92-7
Smiles: CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)C12)C(O)=O
Formula: C30H48O4
Pathway: Apoptosis|||Cytoskeletal Signaling|||NF-Κb|||PI3K/Akt/mTOR signaling
Target: NF-κB|||Akt|||p53
Receptor: N/A
Bioactivity: Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotoxicity against cancer cells.
Molecular Weight: 472, 71
