Product Overview
Alrizomadlin | T14303 | TargetMol Chemicals
CAS: 1818393-16-6
Smiles: CCN1[C@H]([C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc23)C11CCCCC1)C(=O)NC12CCC(CC1)(CC2)C(O)=O
Formula: C34H38Cl2FN3O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: APG-115 (AA-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. APG-115 blocks the interaction of MDM2 and p53. And it induces cell-cycle arrest and apoptosis in a p53-dependent manner[2][3].
Molecular Weight: 642, 59