Product Overview
Altiratinib | T2054 | TargetMol Chemicals
CAS: 1345847-93-9
Smiles: Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)C4CC4)c3)cc2F)cc1
Formula: C26H21F3N4O4
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||Tie-2|||FLT|||Trk receptor|||c-Met/HGFR
Receptor: N/A
Bioactivity: Altiratinib(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro.
Molecular Weight: 510, 473
