Product Overview
AM-0687 | T26607 | TargetMol Chemicals
CAS: 1259522-94-5
Smiles: CNC(=O)c1c(-c2ccccn2)c(nc2ccc(F)cc12)[C@H](C)Nc1ncnc(N)c1C#N
Formula: C23H19FN8O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AM-0687 is a potent and selective PI3Kδ inhibitor. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. Rat KLH: IgG ED50 -= 0.026 mg/kg; IgM ED50 = 0.016 mg/kg. Rat PK Clu = 2.3 L/hr/kg.
Molecular Weight: 442, 458
