Product Overview
AM-1430 | T26608 | TargetMol Chemicals
CAS: T26608
Smiles: CNC(C1=C(C2=NC=CC=C2)C([C@H](C)NC3=NC=NC(N)=C3C#N)=NC4=CC=CC(F)=C14)=O
Formula: C23H19FN8O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AM-1430 is a potent and selective PI3Kδ inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB, u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.
Molecular Weight: 442, 46
