Product Overview
Ambrisentan | T1655 | TargetMol Chemicals
CAS: 177036-94-1
Smiles: COC([C@H](Oc1nc(C)cc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1
Formula: C22H22N2O4
Pathway: GPCR/G Protein
Target: Endothelin Receptor
Receptor: N/A
Bioactivity: Ambrisentan is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but has yet to be implicated in cases of clinically apparent acute liver injury.
Molecular Weight: 378, 42
