Product Overview
Amelubant | T14210 | TargetMol Chemicals
CAS: 346735-24-8
Smiles: CCOC(=O)NC(=N)c1ccc(OCc2cccc(COc3ccc(cc3)C(C)(C)c3ccc(O)cc3)c2)cc1
Formula: C33H34N2O5
Pathway: Immunology/Inflammation
Target: LTR
Receptor: N/A
Bioactivity: Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes.
Molecular Weight: 538, 644