Product Overview
AMG-510 racemate | T7328 | TargetMol Chemicals
CAS: T7328
Smiles: CC(C)c1nccc(C)c1-n1c2nc(c(F)cc2c(nc1=O)N1CCN(C[C@@H]1C)C(=O)C=C)-c1c(O)cccc1F
Formula: C30H30F2N6O3
Pathway: GPCR/G Protein|||MAPK
Target: Ras
Receptor: N/A
Bioactivity: AMG-510 is a potent KRAS G12C covalent inhibitor, treatment with AMG 510 led to the regression of KRASG12C tumours and improved the anti-tumour efficacy of chemotherapy and targeted agents.
Molecular Weight: 560, 59
