Product Overview
AMG319 | T6757 | TargetMol Chemicals
CAS: 1608125-21-8
Smiles: C[C@H](Nc1ncnc2[nH]cnc12)c1cc2ccc(F)cc2nc1-c1ccccn1
Formula: C21H16FN7
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K
Receptor: N/A
Bioactivity: AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
Molecular Weight: 385, 406