Product Overview
Aminopterin N-hydroxysuccinimide ester | T25079 | TargetMol Chemicals
CAS: 98457-88-6
Smiles: O=C1CCC(=O)[NH2+]1.CN(c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C([O-])=O)c1cnc2nc(N)nc(N)c2n1
Formula: C23H25N9O7
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Aminopterin N-hydroxysuccinimide ester is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis.
Molecular Weight: 539, 509
