Product Overview
Amyloid Precursor C-Terminal Peptide | TP2177 | TargetMol Chemicals
CAS: TP2177
Smiles: NCC(=O)N[C@@]([H])(C/C1=C/C=C(/O)C=C1)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N2CCC[C@@]2([H])C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C/C3=C/C=C(/O)C=C3)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C/C4=C/C=CC=C4)C(=O)N[C@@]([H])(C/C5=C/C=CC=C5)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC[S]C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)O)[C@@](O)(C)[H]
Formula: C86H118N20O27S1
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. So it is a possible contributor to Alzheimer′s pathogenesis through MAPKs- and NF-κB-dependent astrocytosis.
Molecular Weight: 1896, 04
