Product Overview
(±)-Anatoxin A fumarate | T22478 | TargetMol Chemicals
CAS: 1219922-30-1
Smiles: OC(=O)\C=C\C(O)=O.[H][C@@]12CC[C@@]([H])(N1)C(=CCC2)C(C)=O
Formula: C14H19NO5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: (±)-Anatoxin A fumarate is a natural alkaloid isolated from freshwater cyanobacterium. It is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively. (±)-Anatoxin A fumarate stimulates [3H]-dopamine release from rat striatal synaptosomes with EC50 of 134 nM.
Molecular Weight: 281, 308