(±)-Anatoxin A fumarate | T22478

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(±)-Anatoxin A fumarate | T22478 | TargetMol Chemicals

CAS: 1219922-30-1

Smiles: OC(=O)\C=C\C(O)=O.[H][C@@]12CC[C@@]([H])(N1)C(=CCC2)C(C)=O

Formula: C14H19NO5

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: (±)-Anatoxin A fumarate is a natural alkaloid isolated from freshwater cyanobacterium. It is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively. (±)-Anatoxin A fumarate stimulates [3H]-dopamine release from rat striatal synaptosomes with EC50 of 134 nM.

Molecular Weight: 281, 308

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