Product Overview
Anti-AIF1 Antibody
Antibodies that detect IBA1 can be used in several scientific applications, including Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Flow Cytometry and ELISA.
These antibodies target IBA1 in Human, Rat and Mouse samples. Our IBA1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse, Goat and Rat.
These antibodies have been verified by Relative expression, Cell treatment and Knockout to confirm specificity to IBA1. Find the IBA1 antibody that fits your needs.
Quality Level
100
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
20A12.1, monoclonal
species reactivity
mouse, human, rat
packaging
antibody small pack of 25 μg
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
NP_001614
The allograft inflammatory factor-1 (AIF-1) is a 17 kDa interferon-gamma (IFN-gamma) inducible Ca(2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. AIF-1 is known to be identical with ionized Ca(2+)-binding adaptor 1, microglia response factor-1, and daintain. AIF-1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma.
It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and the activation and function of macrophages. It is also shown to be expressed in macrophages and microglial cells in autominnume disesases such as experimental autoimmune encephalomyelitis, and neuritis and uveitis models.
