Product Overview
Apaziquone | T21316 | TargetMol Chemicals
CAS: 114560-48-4
Smiles: Cn1c(\C=C\CO)c(CO)c2c1C(=O)C=C(N1CC1)C2=O
Formula: C15H16N2O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.
Molecular Weight: 288, 303