Aphadilactone C | TN3428

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TMC-TN3428
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Product Overview

Aphadilactone C | TN3428 | TargetMol Chemicals

CAS: 1522004-70-1

Smiles: C\C(CCC[C@H]1CC[C@](CCC\C(C)=C\[C@@H]2CC(C)=CC(=O)O2)(C2=CC(=O)C(C)(C)O2)C2=C1OC(C)(C)C2=O)=C/[C@@H]1CC(C)=CC(=O)O1

Formula: C40H52O8

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Aphadilactone C shows significant antimalarial activity with the IC50 value of 170 ± 10 nM. It shows potent and selective inhibition against the diacylglycerol O-acyltransferase-1 (DGAT-1) enzyme (IC50 = 0.46 ± 0.09 uM, selectivity index > 217).

Molecular Weight: 660, 83

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