Product Overview
Apitolisib | T1916 | TargetMol Chemicals
CAS: 1032754-93-0
Smiles: c12sc(CN3CCN(C(=O)[C@@H](O)C)CC3)c(C)c1nc(c1cnc(N)nc1)nc2N1CCOCC1
Formula: C23H30N8O3S
Pathway: Apoptosis|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||PI3K|||mTOR
Receptor: N/A
Bioactivity: Apitolisib, an effective, class I PI3K inhibitor for PI3Kα（IC50=5 nM）, PI3Kβ（IC50=27 nM）, PI3Kδ（IC50=7 nM）, PI3Kγ （IC50=14 nM）, is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others.
Molecular Weight: 498, 6
