Product Overview
Aplaviroc hydrochloride | T26642 | TargetMol Chemicals
CAS: 461023-63-2
Smiles: Cl.CCCCN1C(=O)[C@H](NC(=O)C11CCN(Cc2ccc(Oc3ccc(cc3)C(O)=O)cc2)CC1)[C@H](O)C1CCCCC1
Formula: C33H44ClN3O6
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
Molecular Weight: 614, 18
