Product Overview
Aplaviroc | T14307 | TargetMol Chemicals
CAS: 461443-59-4
Smiles: CCCCN1C(=O)[C@H](NC(=O)C11CCN(Cc2ccc(Oc3ccc(cc3)C(O)=O)cc2)CC1)[C@H](O)C1CCCCC1
Formula: C33H43N3O6
Pathway: Immunology/Inflammation|||Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||CCR
Receptor: N/A
Bioactivity: Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
Molecular Weight: 577, 722
