Product Overview
APY29 | T3654 | TargetMol Chemicals
CAS: 1216665-49-4
Smiles: C1CC1c1cc(Nc2ccnc(Nc3ccc4nc[nH]c4c3)n2)n[nH]1
Formula: C17H16N8
Pathway: Cell Cycle/Checkpoint
Target: IRE1
Receptor: N/A
Bioactivity: APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
Molecular Weight: 332, 371
