Product Overview
Ara-G | T36944 | TargetMol Chemicals
CAS: 38819-10-2
Smiles: Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
Formula: C10H13N5O5
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: Nucleoside Antimetabolite/Analog
Receptor: N/A
Bioactivity: Ara-G is a deoxyguanosine (GdR) analog and a nucleoside analogue that is rapidly converted by cells of the T lymphoid lineage to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and selective in vitro toxicity to T lymphoblastoid cell lines as well as to freshly isolated leukemia cells from patients with T cell acute lymphoblastic leukemia (ALL).
Molecular Weight: 283, 244
