Product Overview
ARD-2128 | T39695 | TargetMol Chemicals
CAS: 2222111-87-5
Smiles: CC(C)([C@H](C1(C)C)NC(c(cc2)ccc2N2CCN(CC(CC3)CCN3c(cc3)cc(C(N4C(CCC(N5)=O)C5=O)=O)c3C4=O)CC2)=O)[C@H]1Oc(cc1)cc(Cl)c1C#N
Formula: C45H50ClN7O6
Pathway: Endocrinology/Hormones
Target: Androgen Receptor
Receptor: N/A
Bioactivity: ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer [1] .
Molecular Weight: 820, 38
