Product Overview
ARP-100 | T14322 | TargetMol Chemicals
CAS: 704888-90-4
Smiles: CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
Formula: C17H20N2O5S
Pathway: Proteases/Proteasome
Target: MMP
Receptor: N/A
Bioactivity: ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 Ī¼M), MMP-3 (4.5 Ī¼M), MMP-7 (>50 Ī¼M), and MMP-9 (0.2 Ī¼M)[1][2]. ARP-100 interacts with S1ļ¼ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel.
Molecular Weight: 364, 42
