Product Overview
ARV-771 | T5435 | TargetMol Chemicals
CAS: 1949837-12-0
Smiles: CC(NC(=O)C1CC(O)CN1C(=O)C(NC(=O)COCCCOCCNC(=O)CC1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C
Formula: C49H60ClN9O7S2
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively[1].
Molecular Weight: 986, 65
