Product Overview
AS-2444697 | T4299 | TargetMol Chemicals
CAS: 1287665-60-4
Smiles: O=C(C1=COC(C2=CC(C)=NC=C2)=N1)NC3=CN(C4CCOCC4)N=C3C(N)=O.[H]Cl
Formula: C19H21ClN6O4
Pathway: Immunology/Inflammation|||NF-Κb
Target: IRAK
Receptor: N/A
Bioactivity: AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
Molecular Weight: 432, 86