Product Overview
AS1810722 | T9043 | TargetMol Chemicals
CAS: 909561-15-5
Smiles: O=C(N)CN1CCN(C2=CC=C(NC3=NC=C4C(N(CC5=CC(F)=CC(F)=C5)C=C4)=N3)C=C2)CC1
Formula: C25H25F2N7O
Pathway: JAK/STAT signaling|||Metabolism|||Stem Cells
Target: P450|||STAT
Receptor: N/A
Bioactivity: AS1810722 is an orally active and potent STAT6 inhibitor(IC50 :1.9 nM). AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research.
Molecular Weight: 477, 52