Product Overview
Asciminib | T5177 | TargetMol Chemicals
CAS: 1492952-76-7
Smiles: O[C@@H]1CCN(C1)c1ncc(cc1-c1cc[nH]n1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1
Formula: C20H18ClF2N5O3
Pathway: Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: Bcr-Abl
Receptor: N/A
Bioactivity: Asciminib (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).
Molecular Weight: 449, 84