Product Overview
AT9283 | T3068 | TargetMol Chemicals
CAS: 896466-04-9
Smiles: O=C(NC1CC1)Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1
Formula: C19H23N7O2
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||FLT|||JAK|||Bcr-Abl|||Aurora Kinase|||Autophagy
Receptor: N/A
Bioactivity: AT9283 is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Molecular Weight: 381, 44
