Product Overview
Atecegatran metoxil | T30192 | TargetMol Chemicals
CAS: 433937-93-0
Smiles: CONC(=N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)[C@H](O)c2cc(Cl)cc(OC(F)F)c2)cc1
Formula: C22H23ClF2N4O5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Atecegatran Metoxil (Atecegatran Fexenetil, AZD0837) is an oral direct thrombin inhibitor, which currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. AZD0837 is a selective and reversible direct thrombin inhibitor and is a bioconverted to AR-H067637.AZD0837 is well tolerated in healthy male subjects at a single oral dose (15-750 mg) and demonstrated favorable PK properties and reproducible effects on in vitro coagulation time variables, supporting further clinical development.
Molecular Weight: 496, 9
