Product Overview
Atractylenolide I | T5S0167 | TargetMol Chemicals
CAS: 73069-13-3
Smiles: CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C=C2OC1=O
Formula: C15H18O2
Pathway: Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||Immunology/Inflammation|||JAK/STAT signaling|||Stem Cells
Target: IL Receptor|||TNF|||TLR|||JAK|||STAT
Receptor: N/A
Bioactivity: 1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88(+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.
Molecular Weight: 230, 307
