Product Overview
Aumitin | T14346 | TargetMol Chemicals
CAS: 946293-78-3
Smiles: Cc1cc(Nc2ccccc2)nc(Nc2ccc(NC(=O)c3ccccc3Cl)cc2)n1
Formula: C24H20ClN5O
Pathway: Autophagy|||Others
Target: Others|||Autophagy
Receptor: N/A
Bioactivity: Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 Ī¼M and 0.24 Ī¼M, respectively[1], and it inhibits mitochondrial respiration by targeting complex I.
Molecular Weight: 429, 91