Product Overview
Aurora kinase inhibitor-3 | T5524 | TargetMol Chemicals
CAS: 879127-16-9
Smiles: FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
Formula: C21H18F3N5O
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Target: Aurora Kinase
Receptor: N/A
Bioactivity: Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
Molecular Weight: 413, 404