Aurora kinase inhibitor-3 | T5524

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TMC-T5524
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Product Overview

Aurora kinase inhibitor-3 | T5524 | TargetMol Chemicals

CAS: 879127-16-9

Smiles: FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1

Formula: C21H18F3N5O

Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic

Target: Aurora Kinase

Receptor: N/A

Bioactivity: Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

Molecular Weight: 413, 404

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