Product Overview
Auten-99 HBr | T26684 | TargetMol Chemicals
CAS: 1049780-58-6
Smiles: Br.C1CN2C=C(SC2=N1)c1ccc(cc1)-c1ccccc1
Formula: C17H15BrN2S
Pathway: Metabolism
Target: Phosphatase
Receptor: N/A
Bioactivity: Auten-99 HBr is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate through the blood-brain barrier, and impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson’s and Huntington’s diseases. Furthermore, the molecule increases the survival of isolated neurons under normal and oxidative stress-induced conditions. Thus, AUTEN-99 serves as a potent neuroprotective drug candidate for preventing and treating diverse neurodegenerative pathologies, and may promote healthy aging.
Molecular Weight: 359, 29
