Product Overview
Avacopan | T8223 | TargetMol Chemicals
CAS: 1346623-17-3
Smiles: Cc1ccc(NC(=O)[C@H]2CCCN([C@H]2c2ccc(NC3CCCC3)cc2)C(=O)c2c(C)cccc2F)cc1C(F)(F)F
Formula: C33H35F4N3O2
Pathway: Immunology/Inflammation
Target: Complement System
Receptor: N/A
Bioactivity: Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV.
Molecular Weight: 581, 656