Product Overview
Avadomide HCl | T26688 | TargetMol Chemicals
CAS: 1398053-45-6
Smiles: Cl.Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O
Formula: C14H15ClN4O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Avadomide is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Ikaros and Aiolos in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects.
Molecular Weight: 322, 75
