Product Overview
Avapritinib | T5109 | TargetMol Chemicals
CAS: 1703793-34-3
Smiles: Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(N)c1ccc(F)cc1
Formula: C26H27FN10
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: PDGFR|||c-Kit
Receptor: N/A
Bioactivity: Avapritinib is a dual inhibitor of the mutant KIT receptor (KIT D816V, IC50: 0.27 nM) and PDGFRα (PDGFRα D842V, IC50: 0.24 nM).
Molecular Weight: 498, 57