Avasimibe | T2753

(No reviews yet) Write a Review
€142.00 - €695.00
SKU:
TMC-T2753
Availability:
IN STOCK
Adding to cart… The item has been added

Product Overview

Avasimibe | T2753 | TargetMol Chemicals

CAS: 166518-60-1

Smiles: CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

Formula: C29H43NO4S

Pathway: Metabolism

Target: P450|||Acyltransferase

Receptor: N/A

Bioactivity: Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM).

Molecular Weight: 501, 73

Reviews

(No reviews yet) Write a Review