Product Overview
Axitinib | T1452 | TargetMol Chemicals
CAS: 319460-85-0
Smiles: CNC(=O)c1ccccc1Sc1ccc2c(\C=C\c3ccccn3)n[nH]c2c1
Formula: C22H18N4OS
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||PDGFR|||c-Kit
Receptor: N/A
Bioactivity: Axitinib is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
Molecular Weight: 386, 47
