Product Overview
AZ-23 | T14363 | TargetMol Chemicals
CAS: 915720-21-7
Smiles: CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1
Formula: C17H19ClFN7O
Pathway: Tyrosine Kinase/Adaptors
Target: Trk receptor
Receptor: N/A
Bioactivity: AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.
Molecular Weight: 391, 84
