Product Overview
AZ-4217 | T26705 | TargetMol Chemicals
CAS: 1383846-83-0
Smiles: CCn1cc(cc(C)c1=O)[C@@]1(N=C(N)c2c1cccc2F)c1cccc(c1)-c1cncc(c1)C#CC
Formula: C30H25FN4O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.
Molecular Weight: 476, 555
