Product Overview
AZ 628 | T6318 | TargetMol Chemicals
CAS: 878739-06-1
Smiles: Cc1ccc(NC(=O)c2cccc(c2)C(C)(C)C#N)cc1Nc1ccc2ncn(C)c(=O)c2c1
Formula: C27H25N5O2
Pathway: Apoptosis|||MAPK
Target: Apoptosis|||Raf
Receptor: N/A
Bioactivity: AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
Molecular Weight: 451, 53
