Product Overview
AZ1495 | T14367 | TargetMol Chemicals
CAS: 2196204-23-4
Smiles: C1CC(CCO1)c1c[nH]c2ncnc(NC3CCC(CC3)N3CCOCC3)c12
Formula: C21H31N5O2
Pathway: Cell Cycle/Checkpoint|||Immunology/Inflammation|||NF-Κb
Target: IRAK|||CDK|||Haspin Kinase
Receptor: N/A
Bioactivity: AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
Molecular Weight: 385, 512