Product Overview
AZ9482 | T22264 | TargetMol Chemicals
CAS: 1825345-33-2
Smiles: O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Formula: C26H22N6O2
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: PARP
Receptor: N/A
Bioactivity: AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
Molecular Weight: 450, 502