Product Overview
AZD-8055 | T1859 | TargetMol Chemicals
CAS: 1009298-09-2
Smiles: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C
Formula: C25H31N5O4
Pathway: Apoptosis|||Autophagy|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1, 000-fold selective for mTOR over all PI3K isoforms.
Molecular Weight: 465, 54