Product Overview
AZD-9164 bromide | T26724 | TargetMol Chemicals
CAS: 1034916-72-7
Smiles: [Br-].C[C@@](N1CCCCC1)(C(=O)O[C@H]1C[N+]2(CCc3ccc(F)cc3)CCC1CC2)c1ccccc1
Formula: C29H38BrFN2O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: AMG-221 is a potent and selective 11β-HSD1 inhibitor. AMG 221 potently blocked 11β-HSD1 activity, producing sustained inhibition for the 24-hour study duration as measured in ex vivo adipose samples. AMG-221 decreased fed blood glucose and insulin levels and reduced body weight in diet-induced obesity mice.
Molecular Weight: 545, 537
