AZD4320 | T14376

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TMC-T14376
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Product Overview

AZD4320 | T14376 | TargetMol Chemicals

CAS: 1357576-48-7

Smiles: CN(CCO)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](O)c1ccccc1-c1ccc(Cl)cc1

Formula: C45H48ClF3N4O7S3

Pathway: Apoptosis

Target: BCL

Receptor: N/A

Bioactivity: AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM, respectively.

Molecular Weight: 945, 53

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