Product Overview
AZD9898 | T14387 | TargetMol Chemicals
CAS: 2042347-69-1
Smiles: COc1nc(cnc1C(=O)[C@H]1C[C@@H]1C(O)=O)N(CC(C)(C)F)c1cc(Cl)c(F)cc1F
Formula: C20H19ClF3N3O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 has the potential to treat asthma[1]. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
Molecular Weight: 457, 83