Product Overview
Azvudine | T14489 | TargetMol Chemicals
CAS: 1011529-10-4
Smiles: Nc1ccn([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]2F)c(=O)n1
Formula: C9H11FN6O4
Pathway: Microbiology/Virology|||Proteases/Proteasome
Target: HCV Protease|||HBV|||HIV Protease|||Reverse Transcriptase
Receptor: N/A
Bioactivity: Azvudine is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
Molecular Weight: 286, 223