Product Overview
Bafetinib | T6311 | TargetMol Chemicals
CAS: 859212-16-1
Smiles: CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncnc3)c2)C1
Formula: C30H31F3N8O
Pathway: Angiogenesis|||Autophagy|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: Bcr-Abl|||Src|||Autophagy
Receptor: N/A
Bioactivity: Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
Molecular Weight: 576, 62
